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How Long Does RitalinĀ® Last?

Why is RitalinĀ® Prescribed?

Methylphenidate (RitalinĀ®) is a medication that is commonly prescribed to treat attention deficit hyperactivity disorder (ADHD) in both pediatric and adult patients. RitalinĀ® is a central nervous system (CNS) stimulant that works by increasing the levels of dopamine and norepinephrine in the brain. This helps to improve focus, increase attention span, and reduce hyperactivity and impulsivity in individuals with ADHD.

RitalinĀ® is sometimes also prescribed for narcolepsy, a sleep disorder characterized by excessive daytime sleepiness and sudden ā€œattacksā€ of sleep.

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How Long Does it Take For RitalinĀ® to Start Working?

The onset of action for RitalinĀ® depends on the formulation and the individual. Immediate-release formulations typically start working within 30- 60 minutes of administration, while extended-release formulations may take 1-2 hours.

How long RitalinĀ® takes to start working can also be affected by the dosage, individual metabolism, and the presence of food or other medications in the body.

How Long Do the Effects of RitalinĀ® Last?

The effects of RitalinĀ® vary depending on several factors, including the individualā€™s physiology and the dosage. However, the typical duration of action of immediate release RitalinĀ® is 3-4 hours and extended-release (ER) form can last up to 8-12 hours.

Immediate release RitalinĀ® reaches peak concentration in the blood between 1-2 hours after taking the medication, while extended-release RitalinĀ® releases medication at an equal pace, providing a more sustained effect throughout the day.

Does the Dosage of RitalinĀ® Affect How Long It Lasts?

The dosage of RitalinĀ® can affect its duration of action. Higher doses of RitalinĀ® can lead to a longer duration of action, however, the actual duration of the medicationā€™s effects can still vary depending on individual factors.

Typical duration of effects of RitalinĀ® are as follows*:

Dosage Duration of Effects
5-10 mg 2-4 hours
10-20 mg 3-4 hours
20-30 mg 4-6 hours
30-40 mg 6-8 hours
40-60 mg 8-10 hours
60-80 mg 10-12 hours

*These are only approximations. Every individual responds to medications differently. 

RitalinĀ® vs. Other ADHD Medications: How Long Do They Last [Comparison Chart]

How long does RitalinĀ® last as compared to other ADHD medications? Weā€™ve broken down the average durations of several popular ADHD drugs below.

Medication Duration of Effects
RitalinĀ® Immediate Release 3-4 Hours
RitalinĀ® Extended Release 8-12 Hours
ConcertaĀ® 10-12 Hours
AdderallĀ® Immediate Release 4-6 Hours
AdderallĀ® Extended Release 10-12 Hours
VyvanseĀ® 10-12 Hours
FocalinĀ® Immediate Release 3-4 Hours
FocalinĀ® Extended Release 8-12 Hours

ADHD medications are not interchangeable. It is important that you do not take medication that has not been prescribed to you even if you have run out of your medication.

What Factors Impact How Long RitalinĀ® Lasts?

Several factors can impact how long RitalinĀ® lasts.

These factors include:

Age

Older adults may experience longer-lasting effects of RitalinĀ® compared to younger individuals due to changes in metabolism and elimination.

Weight & Metabolism

An individualā€™s body weight influences the drug metabolism and absorption, which can impact how long the effects of RitalinĀ®ā€“and other drugsā€“last.

Underlying Conditions

Certain medical conditions, such as diseases of the liver or kidneys, can affect how RitalinĀ® is metabolized by the body and the duration of the drugā€™s effects.

Other Medications

Taking other medications or substances concurrently with RitalinĀ® and impact its duration of effects.

Food and Drink

Consuming food or drink along with RitalinĀ® can impact how quickly it is absorbed and metabolized.[1]

How Long Does RitalinĀ® Stay in the Body?

The half-life of RitalinĀ® is approximately 3.5 hours[2], which means that it takes this amount of time for half of the drug to be eliminated from the body. RitalinĀ®ā€™s effects can last longer than the half life, particularly with extended-release formulations.

RitalinĀ® is detectable in urine for up to 3 days after last use.

Do You Crash After Taking RitalinĀ®?

Some individuals may experience what is called a ā€œRitalinĀ® crash[3]ā€ after the effects of the drug have worn off. This ā€œcrashā€ can feel more intense if the individual has taken a higher dosage or for an extended period.

Signs of ā€œRitalinĀ® crashā€ may include fatigue, irritability, and depression. Not everyone experiences a crash, and the severity and duration of the crash varies among individuals.

How Long Do RitalinĀ® Side Effects Last?

How long RitalinĀ® side effects last depend on the individual, dosage, and formulation. Typically, immediate-release RitalinĀ® causes shorter-lived side effects while extended-release formulations may cause longer-lasting side effects.

If your side effects are severe, it is important to speak with your prescriber.

How Do You Come Down From RitalinĀ® Fast?

If you have been taking RitalinĀ® for an extended period or in high dosages, abrupt cessation or a sudden decrease in dosage can result in withdrawal symptoms which may have adverse effects. Tapering from RitalinĀ® should be done under the supervision of a medical provider.

If you have taken more than the recommended dosage of the medication, or you have taken RitalinĀ® recreationally and are experiencing negative side effects, seek emergency medical attention right away.

Treatment for RitalinĀ® Addiction

Whether you have been prescribed RitalinĀ® to treat symptoms of ADHD or have taken it without a prescription, RitalinĀ® has a high abuse potential.

Life without RitalinĀ® abuse is possible, and help is available.

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At Absolute Awakenings, we take information integrity seriously. We have dedicated our resources to ensure that all content published to our blog is medically sound. As such, all content on our blog has been thoroughly reviewed by a doctorate level clinician such as a Medical Doctor, or Psy.D, so that you can trust all of the data we publish.

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